Fragments of p97 and uses thereof
WebProvided are fragments of human p97 (melanotransferrin) polypeptides having blood-brain barrier (BBB) transport activity, including variants and combinations thereof, conjugates … WebTraductions en contexte de "p97" en français-anglais avec Reverso Context : Description détaillée dans hal-01649595, p97, parag IV.. Traduction Context Correcteur Synonymes Conjugaison Conjugaison Documents Dictionnaire Dictionnaire Collaboratif Grammaire Expressio Reverso Corporate
Fragments of p97 and uses thereof
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WebProvided are fragments of human p97 (melanotransferrin) polypeptides having blood-brain barrier (BBB) transport activity, including variants and combinations thereof, conjugates comprising said p97 fragments, and related methods of use thereof, for instance, to facilitate delivery of therapeutic or diagnostic agents across the BBB. WebUS-9364567-B2 chemical patent summary.
WebComplete Patent Searching Database and Patent Data Analytics Services. WebProvided are fragments of human p97 (melanotransferrin) polypeptides having blood-brain barrier (BBB) transport activity, including variants and combinations thereof, conjugates comprising the p97 fragments, and related methods of use thereof, for instance, to …
WebTo measure p97 at the surface of intact cells, radiolabeled Fab fragments of a monoclonal antibody specific for p97 were used in a binding assay. To measure p97 in detergent-solubilized membrane preparations, we used a novel double-determinant immunoassay that uses two monoclonal antibodies to two distinct antigenic determinants of p97. WebProvided are fragments of human p97 (melanotransferrin) polypeptides having blood-brain barrier (BBB) transport activity, including variants and combinations thereof, conjugates comprising the p97 fragments, and related methods of use thereof, for instance, to facilitate delivery of therapeutic or diagnostic agents across the BBB.
WebNov 10, 2016 · The conjugate of claim 60, wherein the p97 fragment has one or more terminal cysteines and/or tyrosines. 62. The conjugate of claim 60, wherein the antibody or antigen-binding fragment thereof is trastuzumab, or a fragment or variant thereof that specifically binds to human Her2/neu. 63.
WebThe present invention is related to fragments of human melanotransferrin (p97). In particular, this invention relates to treatment of diseases through the introduction of the melanotransferrin fragment conjugated to a therapeutic or diagnostic agent to a subject. ... Or Fragment Thereof With Nonimmunoglobulin Material US Patent Application for ... click to pay checkoutWebUS-2024008929-A1 chemical patent summary. click to pay bmoWebUS-2024008929-A1 chemical patent summary. click to pay csobWebNov 10, 2024 · p97 is an essential ATPase associated with various cellular activities (AAA +) that functions as a segregase in diverse cellular processes, including the maintenance of proteostasis. p97 interacts with different cofactors that target it to distinct pathways; an important example is the deubiquitinase ataxin3, which collaborates with p97 in … click to pay credit card paymentWebpatentimages.storage.googleapis.com bnpl government consultationWebProvided are fragments of human p97 (melanotransferrin) polypeptides having blood-brain barrier (BBB) transport activity, including variants and combinations thereof, conjugates comprising said p97 fragments, and related methods of use thereof, for instance, to facilitate delivery of therapeutic or diagnostic agents across the BBB. bnpl growth 2022WebProvided are fragments of human p97 (melanotransferrin) polypeptides having blood-brain barrier (BBB) transport activity, including variants and combinations thereof, conjugates comprising said p97 fragments, and related methods of use thereof, for instance, to facilitate delivery of therapeutic or diagnostic agents across the BBB. bnpl groceries